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📖 Aktuelle Veröffentlichungen
📰 Der Pathologe – Ausgabe 46, Heft 4 (Juli 2025)
Schwerpunktthema: Recht und Begutachtung
- Granulomatöse Reaktion auf Dermalive-Filler
Michael Bento Schmid, Natalja Denisjuk - Recht und Begutachtung
Matthias M. Gaida, Wilfried Roth - Risikofeld „Fehldiagnose“ – Strafbarkeitsrisiken und Verhaltenstipps in der pathologischen Praxis
Vincent Burgert - Urheber- und datenschutzrechtliche Aspekte zur Nutzung von Bildern aus der Pathologie in Social Media
Carola Sieling, Mareike Julia von Petersdorff-Campen - Histopathologische Diagnostik bei Begutachtungsfragen von Tendo‑, Ligamento- und Meniskuspathologien
Veit Krenn, Lara Blümke, Ralf Dieckmann - Pathologien von Gelenkendoprothesen
Veit Krenn, Lara Blümke, Daniel Klüß - Rechtliche und organisatorische Aspekte der Obduktion in Deutschland
B. Märkl, T. Schaller - Erratum zu: Können wir trotz des rasanten Fortschritts ... Generalist*innen bleiben?
Beatrix Zeller - Atypische Mykobakteriose der Haut
Anna Vetter, Hilte Geerdes-Fenge, Anne-Sophie Becker - Adultes Rhabdomyom
Marvin Seidel, Martin Bredt, Nora Schaumann - Erratum zu: Molekularpathologie des nichtkleinzelligen Lungenkarzinoms ...
Helen Pasternack, Jutta Kirfel - Neues WHO Reporting System for Lung Cytopathology
Marianne Engels
📰 Modern Pathology – Ausgabe 38, Heft 7 (Juli 2025)
Schwerpunktthema: –
- Toward Optimizing the Impact of Digital Pathology and Augmented Intelligence on Issues of Diagnosis, Grading, Staging, and Classification
Lewis A. Hassell et al. - A Multicenter Study on Intraoperative Glioma Grading via Deep Learning on Cryosection Pathology
Xi Liu et al. - Spatial Expression of HER2, NECTIN4, and TROP‑2 in Muscle‑Invasive Bladder Cancer and Metastases: Implications for Pathological and Clinical Management
Gabriel Dernbach et al. - RNA In Situ Hybridization Detection of CRTC1/3::MAML2 Fusions and LINC00473 in Mucoepidermoid Carcinomas and Hidradenomas...
Cooper D. Rutland et al. - A Deep Learning Model of Histologic Tumor Differentiation as a Prognostic Tool in Hepatocellular Carcinoma
Ameya Patil et al. - Lower Degree of Microsatellite Instability in Colorectal Carcinomas From MSH6-Associated Lynch Syndrome Patients
Noah C. Helderman et al. - Multiregion Genomic Analysis of Human Pancreatic Mucinous Cystic Neoplasms
Michael J. Pflüger et al. - Nosologic Reappraisal of the Recently Proposed Calcified Chondroid Mesenchymal Neoplasm Concept...
Shogo Nishino et al. - Methylation Analysis Reveals Epigenetic Congruence Between Bone Sarcomas With H3‑3A Mutations and Malignant Giant Cell Tumors of Bone
Carla Saoud et al. - Labor‑Efficient Pathological Auxiliary Diagnostic Model for Primary and Metastatic Tumor Tissue Detection in Pancreatic Ductal Adenocarcinoma
Xinyi Ke et al. - Cytoplasmic p53 Immunostaining in Salivary Duct Carcinoma: A Poor Prognostic Factor Associated With Characteristic TP53 Variants
Yoshitaka Utsumi et al. - Spatially Resolved Single‑Cell Morphometry of Benign Breast Disease Biopsy Images Uncovers Predictive Features for Subsequent Invasive Breast Cancer Risk
Mustapha Abubakar et al. - AI‑Based Single‑Cell Analysis as a Next‑Generation Histologic Grading Approach in Colorectal Cancer
Vincenzo Mitchell Barroso et al. - Meningiomas With Chromosomal Polysomies Reveal Nonrandom Gain of Chromosomes, Distinct Methylation Signature...
Erica Vormittag‑Nocito et al. - Not All HER2‑Positive Breast Cancers Are the Same: Intratumoral Heterogeneity, Low‑Level HER2 Amplification...
Wenli Dai et al. - Contemporary Approach to the Diagnosis and Classification of Myelodysplastic Neoplasms/Syndromes: Concerns and Issues
M. Tarek Elghetany - Contemporary Approach to the Diagnosis and Classification of Myelodysplastic Neoplasms/Syndromes: Authors’ Response
Fnu Aakash, Sanam Loghavi - First Cases of NUT Carcinoma Harboring NUTM2 Gene Rearrangements
Mark G. Evans et al.
📰 The American Journal of Pathology – Ausgabe 195, Heft 8 (August 2025)
- This Month in AJP
Published online: June 12, 2025 - Discovery and Mechanistic Insights into Vascular Permeability Factor/Vascular Endothelial Growth Factor through the Work of Harold F. Dvorak and Ann M. Dvorak
Stephen J. Galli, August 2025 - The Angiofibrotic Switch in Retinal and Choroidal Vascular Diseases
Fergus C. McLellan et al., June 02, 2025 - Exploratory Study of Prognostic Plasma Biomarkers in Patients with Pulmonary Arterial Hypertension
Yukimitsu Kuwabara et al., May 29, 2025 - Autocrine Transforming Growth Factor-β Signaling Promotes Cell Motility and Chemokine Secretion in an Angiomyolipoma-Derived Cell Model of Lymphangioleiomyomatosis
Anna Moskal et al., May 30, 2025 - Phosphatidylinositol 3-Kinase Signaling Enhances Intestinal Crypt Epithelial Cell Recovery after Radiation
Evan B. Lynch et al., April 30, 2025 - Notch Signaling Aggravates Helicobacter pylori–Induced Inflammation by Promoting Macrophage Activation and Proinflammatory Th1/Th17 Responses
Yunxuan He et al., April 30, 2025 - Mitochondrial Protease AFG3L2 Inhibits Ferroptosis of Intestinal Epithelial Cells through PPARA/GPX4 Signaling Pathway to Improve Experimental Enteritis
Wei Chen et al., May 29, 2025 - Severe Acute Respiratory Syndrome Coronavirus 2, the Human Placenta, and Adverse Perinatal Outcomes
Rebecca L. Linn et al., April 29, 2025 - Collagen VII Is Associated with Airway Remodeling, Honeycombing, and Fibroblast Foci in Usual Interstitial Pneumonia/Idiopathic Pulmonary Fibrosis
Barbora Svobodová et al., April 29, 2025 - Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 Drives Subchondral Bone Damage in Temporomandibular Joint Osteoarthritis through Peroxisome Proliferator-Activated Receptor γ/Cellular FOS Proto-oncogene–Regulated Dual Pathways
Ziyan Jiang et al., April 30, 2025 - FKBP10 Silencing Alleviates Gluteal Muscle Contracture by Inhibiting Fibrosis and Restoring Autophagy via HSP47/SMAD3 Pathway Inactivation
Haixia Xu et al., April 30, 2025 - The Long Noncoding RNA TUG1 Is Down-Regulated in Osteonecrosis of the Femoral Head and Enhances the Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells by Stimulating the Wnt/β-Catenin Pathway
Xudong Duan et al., August 2025 - Pharmacologic Inhibition of Glutamate Dehydrogenase 1 Improves Functional Recovery of Neuromuscular Junctions and Muscle Function in Duchenne Muscular Dystrophy
Andreia Pereira-Nunes et al., June 01, 2025 - Identification of a Growth-Promoting Gene Cluster in the Region 2q24 as a Driver of Tumorigenesis in Childhood Hepatoblastoma
Martin M. Rodemann et al., April 30, 2025 - Correction
Published online: June 04, 2025
📰 Histopathology – Ausgabe 87, Heft 2 (August 2025)
- Malignant phyllodes tumours of the breast: The case for revising WHO’s ‘full house’ diagnostic criteria
Puay Hoon Tan, Ian O. Ellis, Kimberly H. Allison, Sunil S. Badve, Edi Brogi, Grace Callagy, Emmanuelle Charafe‐Jauffret, Chih‐Jung Chen, Yunn‐Yi Chen, Laura C. Collins, Gábor Cserni, ... Emad A. Rakha - Data set for reporting paediatric renal tumours: Recommendations from the International Collaboration on Cancer Reporting (ICCR)
E. J. Perlman, F. Webster, K. T. E. Chang, A. Coulomb, L. Galluzzo, N. S. Graf, E. A. Mullen, H. Okita, M. J. O’Sullivan, G. R. Somers, A. Treece, M. Cohen, M. Reyes-Múgica - Atypical spindle cell/pleomorphic lipomatous tumour: A clinicopathologic, immunohistochemical and molecular study of 55 cases, highlighting TP53 gene alterations as a genetic hallmark
Fleur Cordier, Tony G. Kleijn, Thomas Mentzel, Uta Flucke, Joost van Gorp, Liesbeth Ferdinande, Sarah Van Belle, Siebe Loontiens, Joni Van der Meulen, Jo Van Dorpe, Arjen H. G. Cleven, David Creytens - Current practices in prostate pathology reporting: Results from a survey of genitourinary and general pathologists
Mahra Nourbakshs, Liping Du, Andres M. Acosta, Reza Alaghehbandan, Ali Amin, Mahul B. Amin, Manju Aron, Daniel Berney, Fadi Brimo, Emily Chan, Liang Cheng, ... Giovanna A. Giannico - ROS1 immunohistochemistry as a potential predictive biomarker for ROS1-targeted therapy in breast cancer: Impact of antibody clone selection
Anna Sokolova, Vaibhavi Joshi, Haarika Chittoory, Michael Walsh, Malcolm Lim, Jamie R. Kutasovic, Kaltin Ferguson, Peter T. Simpson, Sunil R. Lakhani, Amy E. McCart Reed - Clinicopathological features of microinvasive lobular carcinoma
Rachel Han, Atif A. Hashmi, Hannah Y. Wen, Melissa Murray, M. Gabriela Kuba, Andrew D. Seidman, Monica Morrow, Edi Brogi - DCIS-like invasive carcinoma of the breast with tumour-associated microvasculature mimicking myoepithelium: A diagnostic pitfall
Taylor Salisbury, Mara Rendi, Rabia Bhalli, Gregory R. Bean, Kimberly H. Allison, Megan L. Troxell - Morphological, immunohistochemical and molecular analysis of follicular dendritic cell sarcomas: L1CAM as a new diagnostic marker
Selina Schelbert, Katja Maurus, Sabine Roth, German Ott, Katrin S. Kurz, Carolin Mogler, Barbara Wollenberg, John Linde, Alberto Zamo, Ioannis Anagnostopoulos, Susanne Gramlich, Andreas Rosenwald, Elena Gerhard-Hartmann - Unveiling the molecular landscape and clinically relevant molecular heterogeneity of mucosal melanoma of the head and neck region
Costantino Ricci, Maria Vittoria Altavilla, Dario de Biase, Barbara Corti, Ernesto Pasquini, Gabriele Molteni, Achille Tarsitano, Anna Maria Baietti, Luca Amorosa, Francesca Ambrosi, Tiziana Balbi, ... Stephan Ihrler, Maria Pia Foschini - The first reported case of effective targeted therapy in extrahepatic cholangiocarcinoma harboring an epidermal growth factor receptor exon 19 deletion
Ling-Jen Hung, Shih-Chiang Huang, Chih-Wei Wang, Wen-Kuan Huang, Ching-Fu Chang - Malignant ossifying fibromyxoid tumour with TP53::PHF1 fusion: Report of three cases suggesting an association between rare fusions and malignant phenotypes
Nathaniel J. Bigot, Azfar Neyaz, Ali Alani, Arivarasan Karunamurthy, Robert D. Bubar, Melissa A. Burgess, Gregory W. Charville, Ivy John - TERT dysregulation through intrachromosomal rearrangement in a skull-based soft tissue myoepithelial carcinoma
Prokopios P. Argyris, Kyle K. VanKoevering, Daniel M. Jones, Steve Oghumu, O. Hans Iwenofu
📰 Human Pathology – Band 161 (Juli 2025)
- Evidence of interstitial continuity within and beyond the human pancreas
Neil D. Theise, Mehran N. Kohnehshahri, Luis A. Chiriboga, Billie Fyfe, Rebecca G. Wells - Clinicopathologic findings in native liver biopsies after heart transplantation and total artificial heart implantation
Michael Kozak, Mahzad Azimpouran, Xiaomo Li, Danielle A. Hutchings, Brent K. Larson - Diagnostic accuracy of TRIM63 RNA-ISH in MiTF-rearranged renal cell carcinomas: Results from a 331-tumor validation cohort
Hyun Jung Lee, Farinaz Shokri, Maria S. Tretiakova - Somatic yolk sac tumors in the urinary tract: A form of rare divergent differentiation
Nicholas Tedrow, Kenneth Ogan, Shreyas Joshi, Mehmet Asim Bilen, Lara Harik - Comparative study of intra- and inter-observer variability in manual scoring of HER2 immunohistochemical stains on glass slides versus paired digital images with emphasis on the low end of the expression spectrum
Andrew Xiao, Poonam Vohra, Yunn-Yi Chen, Leah Ung, Joseph Geradts - Multi-modal convolutional neural network-based thyroid cytology classification and diagnosis
Dandan Yang, Tianlun Li, Lu Li, Shuai Chen, Xiangli Li - BSND: An emerging immunohistochemical marker that reliably distinguishes benign from malignant oncocytic salivary gland tumors
Arshi Tandon, Sabari Sinehaa, Sheeba Saifi, Amit Kumar Adhya, Aanchal Kakkar - Secondary pancreatic tumors in endoscopic ultrasound-guided fine-needle biopsy: Clinicopathologic characteristics and morphological diagnostic challenges
Min Cui, Mohamed Amed, Michelle D. Reid, Yue Xue - Clinicopathologic characteristics of papillary thyroid carcinoma, tall cell subtype and subtype with tall cell features, an institutional experience
Xueting Jin, Shunsuke Koga, Xiao Zhou, Niaz Z. Khan, Zubair W. Baloch - Neoplastic ductal plate malformation pattern rather than von Meyenburg complexes may be an early neoplastic lesion of small duct-type intrahepatic cholangiocarcinoma
Yasuni Nakanuma, Motoko Sasaki, Yuko Kakuda, Kenichi Harada, Takashi Sugino
📚 Laboratory Investigation – Ausgabe 105, Heft 7 (Juli 2025)
- Deep Learning–Powered Whole Slide Image Analysis in Cancer Pathology
Chengrun Dang, Zhuang Qi, Tao Xu, Jie Wu, Yuxin Lin, Xin Qi - Hidden in the Absence: Clinicopathologic Insights on Kidney Diseases Associated With Selective IgA Deficiency
Bangchen Wang, Harpreet Singh, Matthew Ellis, Laura Barisoni, David N. Howell - APOBEC-Driven Hypermutation in the Lymphocyte-Predominant Group of Triple-Negative Breast Cancer
Miseon Lee, Ahwon Lee, Tae-Kyung Yoo, Sung Hun Kim, Jieun Lee, Jun Kang - Inflamed Intestinal Epithelial Cells From Patients With Ulcerative Colitis Restore a Noninflamed Transcriptional Profile Upon In Vitro Expansion
Alexander Due Hammerhøj, Theresa Louise Boye, Jiayi Yao, Casper Steenholdt, Kim Bak Jensen, Ole Haagen Nielsen - Mild Duodenal Mucosal Injury and Increased Type I Interferon Signaling Are Preludes to Celiac Disease
Changqing Ma, Adina K. Bard, Eric Tycksen, Phillip I. Tarr, Lori R. Holtz, Ta-Chiang Liu - Comparison of Fluorescence In Situ Hybridization, Next-Generation Sequencing, and DNA Methylation Microarray for Copy Number Variation Assessment in Gliomas
Jiao Wang, Yang Lan, Hao-Yue Qi, Xiu-Wu Bian, Xiao-Hong Yao, Tao Luo - Role of Reserve Cells in Metaplasia and the Development of Human Papillomavirus–Associated High-Grade Squamous Intraepithelial Lesions at the Cervical Transformation Zone
Ademola Aiyenuro, Heather Griffin, Konstanze Schichl, Silvia de Sanjosé, Mark Schiffman, John Doorbar - EGR1–BDNF–Linking Crosstalk Between Cancer Cells and Nerves for Perineural Invasion in Salivary Duct Carcinoma: Comparison of Salivary Duct Carcinoma De Novo and Ex Pleomorphic Adenoma
Airi Sakyo, Eijitsu Ryo, Seiichi Yoshimoto, Yasushi Yatabe, Fumihiko Matsumoto, Taisuke Mori - Multicenter Evaluation of Certainty and Reliability in Calciphylaxis Diagnosis Using a Digital Imaging Platform
Soma Jobbagy, Emilio Madrigal, Houda Bouchouari, Sagar U. Nigwekar, Rosalynn M. Nazarian, The Calciphylaxis Consensus Working Group - Spatial Analysis Identifies CD147 as a Novel Marker of High-Grade Childhood Posterior Fossa Ependymoma
Donatella Lucchetti, Filomena Colella, Antonio d’Amati, Ivan Masetto, Antonio Ruggiero, Alessandro Sgambato - Corrigendum to “386 Targeted NGS for TP53 and BRCA1, BRCA2, Gene Mutations and Comparison with Immune Cell Profiling and Immune Checkpoint Inhibitor Expression in Ascitic Fluid with Metastases from High Grade Serous Ovarian Carcinoma”
Radhika Srinivasan, Megha Sharma, Amit Sharma, Parikshaa Gupta, Upasana Gautam, Rashmi Bagga
📰 News & Updates
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Neue Glossar-Einträge
Die Glossar-Einträge Giardiasis, Entamoeba histolytica, Mykobakteriose, Mikrosporidiose, Zystoisosporiasis wurden hinzugefügt.
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Die Glossar-Einträge Kryptosporidiose, Leishmaniose, Histoplasmose und Kryptokokkose wurden hinzugefügt.
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Die Glossar-Einträge Grocott-Färbung, Masson-Trichrom-Färbung, Giemsa-Färbung, Kongo-Rot-Färbung wurden hinzugefügt.
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Die Glossar-Einträge HE, PAS, Ziehl-Neelsen-Färbung, EVG wurden hinzugefügt.
HE AI-Upscaler läuft
Im Toolbereich der Menu-Leiste steht ab sofort der KI-gestützte HE-Upscaler für kleine Bilder zur Verfügung. Damit lassen sich HE-Bilder um den Faktor 4 vergrößern. Die Upscale-Technik basiert dabei auf Real-ESRGAN 🔗 und nutzt GPU-unterstützte neuronale Netze. Damit lassen sich oft bessere Ergebnisse erziehlen als mit klassischen Vergrößerungsalgorithmen.
Infektiöse GI-Erkrankungen bei HIV
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